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Among them, Box I and Box II presented among the tomato GST CREs

For example, gestational protein restriction in mice decreased H3K4me3 and H4K20me3 while it increased H3K9me3 and H3K27me3 levels on the Igf2 (Insulin-like growth factor-II) locus, resulting in its repression in fetal liver (Strakovsky et al., 2011)

They found that the insulin-mediated suppression of GH is independent of the IGFIR [5]
