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Borbath and coworkers [82] reported the case of a 51-year-old woman who received 10 mg/kg VPA daily to prevent seizures after a neurosurgical procedure, and who developed VHE (ammonia concentration 234 mol/l) without any sign of hepatic dysfunction
The process of generating ATP naturally produces reactive oxygen species (ROS), which are highly volatile molecules that can cause severe cellular damage if left unchecked
