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A clinical guide to diagnosis and treatment By Dr Phoebe Stanford Published July 2025 Understanding Vitamin D: Function, sources and metabolism Vitamin D is a fat-soluble vitamin which plays a key role in calcium and phosphate homeostasis and is important for bone and muscle function

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These changes are accompanied by decreased NFB signaling and increased NRF2 activation (Innamorato et al., 2008

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Concurrent use is mechanistically redundant and amplifies negative feedback suppression

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In addition to their involvement in the stress response, GCs (cortisol, cortisone, and corticosterone) have several essential biological functions

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