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Description
Resistance to antiangiogenic therapies can be intrinsic, when it is observed at the beginning of the treatment, or acquired, i.e., that it affects the relapsing disease after an initial response to therapy [26,27]

found that the presence of IGF-1 stimulated cell proliferation in rat primordial follicles by measuring the increasing DNA content within the follicular cells (61)
Mechanism of Action GHK-Cu exerts its biological effects through multiple interconnected mechanisms, acting both as a signalling molecule and a copper delivery system

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