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Dominant negative G s (DNG s ) in pFastBac vector, and poly-his tagged G1 and G2 in a single pVL dual vector construct were used as previously described
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Studies indicate that excessive collagen deposition promotes atrial tissue fibrosis, which disrupts the propagation of myocardial impulses and raises the risk of arrhythmia (Akhurst and Hata, 2012)
