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The detoxification process can be roughly divided into three phases [2]: Phase I is governed by transformation enzymes these enzymes oxidize, reduce and hydrolyze toxins/drugs Phase II is managed by conjugation enzymes these enzymes conjugate Phase I products Phase III is carried out by transport proteins these proteins transport the final products from the cell Transporters Eliminate Toxins from Cells ABC Transporters Phase III of detoxification is responsible for eliminating toxins and metabolic products from cells

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Quality control is primarily carried out using high-performance liquid chromatography (HPLC) for purity determination and mass spectrometry (MS) for identity confirmation

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10.1016/j.theriogenology.2003.11.013 28

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Product is provided as a freeze-dried powder within a sterile 2ml vial

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