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Mastrocola RRestivo F, Vercellinatto I, Danni O, Brignardello E, Aragno M, Boccuzzi G

Upregulation of Gadd45a and Cdkn1 induces cell cycle arrest in response to glutamine deprivation, which alleviates oxidative stress and reduces energy consumption 126,127

Melanocytes are cells that make pigment, which is incorporated into the hair shaft, giving hair its distinctive color. When these melanocytes start to reduce and their count is not replenished, the pigment in the hair shaft is also reduced, eventually causing the hair to turn white

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