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doi: 10.1016/j.cell.2018.04.027 224
The ACHIEVE-3 trial demonstrated that orforglipron was superior to oral semaglutide (Rybelsus) in both HbA1c reduction and weight loss in a head-to-head comparison, reducing HbA1c by approximately 2.2 percentage points versus 1.4 points with oral semaglutide, and producing 9.2% weight loss versus 5.3%
Gen 34 , 12171229, (2017)
During breast cancer treatment, anastrozole is used to inhibit the growth of the enzyme aromatase, which causes side effects such as bone fractures and osteoporosis (241, 242)
