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Curcumin potentiates 7 nicotinic acetylcholine receptors and alleviates autistic-like social deficits and brain oxidative stress status in mice

c , The endogenous GPX4 in HT1080 OE GFP-K125R-K127R-GPX4 were tested for vulnerability to the degradation induced by RSL3, ML162, FIN56, and IKE

By directly downregulating SIRT1, miR-34a leads to increased synthesis of inflammatory cytokines, including IL-6, TNF-, IL-1, and IL 8, and oxidative stress proteins, including MCP-1, vascular cell adhesion protein 1 (VCAM1), and MDA, and decreased levels of the anti-inflammatory cytokine IL-10 [297, 303]

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