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The glycerol moiety of the fragment lied adjacent to Leu365, Ser366, Glu410, Glu413, Glu414, and His433, with the side chain of Glu410 capable of forming hydrogen bonds with the hydroxyl groups of glycerol

Intraperitoneal administration of metformin significantly prevented the impairment of peripheral IENFs and mechanical allodynia, as well as the numbness induced by cisplatin in mice

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15mg per dose Primary Benefits Promotes systemic recovery, reduces inflammation throughout the body, and enhances muscle repair through thymosin beta-4 pathways