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Effects of a microinjection of morphine into the amygdala on the acquisition and expression of conditioned fear and hypoalgesia in rats

Proc R Soc Lond B 286:20191917 Plcido A, do Pais do Amaral C, Teixeira C, Nogueira A, Brango-Vanegas J, Alves Barbosa E, Moreira D, Silva-Carvalho A, da Silva MDG, do Nascimento Dias J, Albuquerque P, Saldanha-Arajo F, Lima F, Batagin-Neto A, Kuckelhaus S, Bessa LJ, Freitas J, Dotto Brand G, Santos N, Relvas J, Gomes P, Leite JR, Eaton P (2022) Neuroprotective effects on microglia and insights into the structure-activity relationship of an antioxidant peptide isolated from Pelophylax perezi

doi: 10.1016/s0168-8278(99)80102-0

Additionally, molecular analysis indicated that up-regulation of -arrestin2, an intracellular protein involved in the desensitization and internalization of dopamine receptors and activation of alternative signaling pathways, may be associated with reduced severity of dyskinesia in levodopa-benserazide-loaded PLGA nanocarrier-treated PD rats