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By contrast, the AdV vector formulation generates AdV-specific immunity, which can limit efficacy of repeated boosters owing to immune-mediated clearance of the vector
A Near-Infrared, Wavelength-Shiftable, Turn-on Fluorescent Probe for the Detection and Imaging of Cancer Tumor Cells

doi: 10.3389/fphys.2023.1166685 17

Most of the available studies are small and inconclusive
