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Description
APP undergoes enzymatic cleavage within the brain to form numerous fragments, including A, which accumulates in AD-associated amyloid plaques and COOH-terminal fragments (CTFs) that may impair intracellular processes (464)
20 Abnormal liver blood tests, in particular elevations of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) are commonly seen in clinical care, although the prevalence of clinically significant liver disease is low
BartimocciaSCammisottoVNocellaCDel BenMD'AmicoACastellaniVet al
Epub 2008 Oct 8
