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The absence of MZB-mediated immunity was substantiated by the lack of anti-TNP IgM at 7 days post-immunization with TNP-Ficoll in Gclc fl/fl Mb1-Cre + mice (Supplementary Fig
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As Peg10 is an endogenous protein in mammals, the SEND system exhibits low immunogenicity, which is a potential tool for gene treatment (Fig
