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This rapid degradation means that systemic, long-lasting effects from a single injection are biologically improbable

[DOI] [PMC free article] [PubMed] [Google Scholar] 102.Smith MR, Gangireddy SR, Narala VR, Hogaboam CM, Standiford TJ, Christensen PJ, et al

Protecting mammalian hair cells from aminoglycoside-toxicity: assessing phenoxybenzamine's potential

Indeed, it was clearly shown that the antioxidant N-acetyl-L-cysteine (NAC) can inhibit eryptosis in vitro [116] and significantly prolong the half-life of circulating mouse erythrocytes in vivo [72] presumably by interfering with efferocytosis of eryptotic cells