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A better understanding of these interdependencies could inform novel therapeutic strategies for both acute and post-acute COVID-19

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Mutation in mitochondrial ribosomal protein MRPS22 leads to Cornelia de Lange-like phenotype, brain abnormalities and hypertrophic cardiomyopathy

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Mitochondrial copper homeostasis and its derailment in Wilson disease

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As one research study puts it: It could be that the brain relies primarily on endogenous creatine synthesis until there is some sort of challenge to brain creatine status

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