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Among the seven sirtuins, SIRT1, a nicotinamide adenine dinucleotide (NAD)-dependent deacetylase, is the most extensively studied and has emerged as a central regulator of senescence-related liver changes (Wu et al., 2022)

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These results imply that aSYN might influence vesicle fusion during synaptic stimulation and the distribution of vesicles between the ready releasable and reserve synaptic pools, acting as a negative regulator of dopamine release

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Chronic melatonin therapy fails to alter amyloid burden or oxidative damage in old Tg2576 mice: implications for clinical trials

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