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We also established Drosophila expressing normal length 9 G 4 C 2 repeats as a control [( G 4 C 2 ) 9 flies], and found that they did not show eye degeneration, motor dysfunction, RNA foci formation, or DPR aggregation (Figure 1figure supplement 1)

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Patients can deteriorate quickly with a sudden loss of respiratory control, abrupt swings in vital signs, aspiration, and cardiovascular complications