hepatic glutathione status Frontiers Glutathione disulfide sensitizes hepatocytes to
Description
GSH directly neutralizes reactive oxygen species (ROS), including hydrogen peroxide (HO) and lipid peroxides, and contributes to the detoxification of xenobiotics and electrophilic compounds through conjugation reactions mediated by glutathione S-transferases (GSTs) [36]
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Carter EA: Enhanced acetaminophen toxicity associated with prior alcohol consumption in mice: prevention by N-acetylcysteine
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