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Notably, a golden standard to assess preclinical CLBP is still missing but is urgently needed to substantiate therapeutic efficacy of novel biomolecular therapies for CDLBP

We constructed standardized experimental models encompassing murine full-thickness burn injuries [13], rat dermal incisional wounds [13], and rodent skeletal muscle contusion models (Figure S1)

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Providing treatment without understanding whats going on beneath the surface can do more harm than good
