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In case the ligand is a small molecule, steric hindrance will occur between the immobilized support and the compound of interest (Figure 10)

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Detox Phases The detoxification process can be roughly divided into three phases [3]: Phase I is governed by transformation enzymes these enzymes oxidize, reduce and hydrolyze toxins/drugs Phase II is managed by conjugation enzymes these enzymes conjugate Phase I products Phase III is carried out by transport proteins these proteins transport the final products from the cell Phases I, II, and III must work in unison for the proper removal of unwanted toxins, drugs, and excess hormones

Due to its stability and structure, it has become a subject of interest in controlled laboratory investigations