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Long-term safety of DSIP has not been fully established

As an electron shuttle, MB can substitute for natural cofactors in redox reactions due to its favorable redox potential (Nedu et al

A smaller placebo-controlled trial showed that oral administration of 300 mg/day of coenzyme Q 10 for 48 to 96 months moderately improved motor symptoms in treated patients (with Levodopa) with re-emerging symptoms but not in patients at an early stage of the disease (67)

[DOI] [PMC free article] [PubMed] [Google Scholar] 182.Yip B
