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Some studies have demonstrated significantly reduced serum B 12 as well as macrocytosis in MS patients, while others did not show such an association.[3] The nature of the relation between MS and B 12 deficiency is unclear and multiple levels of inter-relationship may be suggested

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doi: 10.1186/s12915-020-00836-x 141 FerreiraMRMulsADearnaleyDPAndreyevHJN