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Zinc dysregulation within the endolysosomal system also intersects with cancer biology: the alcohol-deterrent and emerging anticancer agent disulfiram disrupts endolysosomal structure and raises intraluminal zinc in breast cancer cells, implicating zinc dysregulation in its cytotoxicity and suggesting that extracellular zinc availability modulates its efficacy 169

McDonald M, Hertz RP, Unger AN, Lustik MB

The most widely grown GM crops express genes that confer herbicide tolerance and insect resistance

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