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Decreased GSH Levels in the Cell: Its Injurious Effects The BSO-induced GSH depletion enhances mitochondrial structural aberrations by affecting the thiol redox potential, which is prevented by the overexpression of BOLA1, a mitochondrial protein [121]

In CRC, this could enhance NK cell-mediated lysis by preserving surface MICA expression (142)

(2011) documented the generation and characterization of a novel NRF2/ARE pathway biosensor fish, which exhibits dynamic spatio-temporal expression profiles during early developmental stages

Pharmacogenetics of modafinil after sleep loss: Catechol-O-methyltransferase genotype modulates waking functions but not recovery sleep