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Conclusion High-resolution ultrasound has improved the diagnosis of brachial plexopathies, and ultrasound-guided perineural injection of vitamin B12 can serve as a treatment approach specific to injured nerves for preoperative or postoperative treatment in cases of post-ganglionic BPI

ADVANCES The past decade has brought numerous advances in our understanding of why tumors develop metabolic phenotypes that differ from adjacent, nonmalignant tissues and when these phenotypes represent actionable therapeutic vulnerabilities

Oral high-dose B12 (1,000-2,000 g daily) may be considered as an alternative for patients with dietary deficiency without malabsorption who prefer this route or cannot tolerate injections

As a novel marker of cancer, ESM1 has been studied extensively