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The role of ascorbic acid in the biosynthesis of the neuroendocrine peptides alpha-MSH and TRH
Safety also requires attention, especially hypercalcemia and mineral imbalance with active agents or bolus regimens
However, in scurvy, vitamin C is retained by the brain for neuronal function, and eventual death from the disease is more likely due to lack of vitamin C for collagen synthesis (44)
Most patients notice improvement in 6-8 weeks but a three-month trial is called for
